L-arginine facilitates the hyperplasia of sebaceous gland in rats
- VernacularTitle:L-精氨酸可致大鼠正常皮肤皮脂腺增生
- Author:
Yanru YIN
;
Fei WANG
;
Xu CAO
- Publication Type:Journal Article
- Keywords:
L-arginine;
nitric oxide;
sebaceous gland;
hyperplasia;
rats
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2004;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effects of L-arginine on sebaceous gland hyperplasia in rats. METHODS: 10 mg?kg -1?d -11 of L-arginine was poured into the stomach in Sprague-Dawley rats for 7-14 d. The pathology phenomenon was observed in the rat skin. RESULTS: The backside skin of the male SD rats showed dewiness, greasiness and engrained yellow. The incidence was 100% for 7 d in the male SD rats, 80% in the female SD rats for 14 d, but 100% in the immature female SD rats for 14 d. CONCLUSION: L-arg nine can facilitate the hyperplasia of sebaceous gland in SD rats.
