The role of bile reflux in pathogenesis of stress ulcer after acute brain trauma in rat
- VernacularTitle:胆汁反流在大鼠急性颅脑损伤后应激性溃疡中的作用
- Author:
Juan WANG
;
Zhaoxu YANG
;
Peilin CUI
- Publication Type:Journal Article
- Keywords:
stress ulcer;
bile reflux;
brain trauma
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the role of bile reflux in the pathogenesis of stress ulcer after acute brain trauma in rat. Methods The animal model was reproduced by Allen's method with modification. The bile acid concentration in the stomach and blood, the pH value of the gastsic content, and ulcer index (UI) were assayed 1, 3, 6, 24 hour after the stress, and they were compared with that of sham injury group. Results In stress group, compared with sham injury group, the amount of bile acid in the stomach was notably increased( P