Treatment for diabetic nephropathy with integrated liposomal prostaglandin E_1 and fosinopril.
- VernacularTitle:前列腺素E_1与福辛普利联合治疗糖尿病肾病疗效分析
- Author:
Hongchu LIN
;
Henglian WU
;
Guohui LIU
- Publication Type:Journal Article
- Keywords:
Liposomal prostaglandin E 1 Fosinopril Diabetic nephropathy Urinaryalbumin excretion rate Renal function
- From:
Chinese Journal of Practical Internal Medicine
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of integrated liposomal prostagladin E 1(Lipo PGE 1) and fosinopril on early diabetic nephropathy (DN) and clinical DN.Methods 86 patients of type 2 diabetic patients with DN were randomly divided into control group (fosinopril) and treated group(fosinopril+Lipo PGE 1).UARE,Scr and BUN figures were compared between two groups before treatment and eight weeks after treatment.Results UAER had been decreased significantly in both groups(P0.05).Furthermore,no significant decrease of BUN、FBG、MPA、TC and TG had been found in both groups.Conclusion Integrated Lipo PGE 1and fosinopril can ameliorate proteinuria and improve renal function of the patients with early DN and clinical DN of normal renal function.
