STUDY ON THE ANTIOXIDATIVE ACTIVITY AND EFFECTS ON EXPERIMENTAL HYPERLIPIDEMIA OF NATTO EXTRACT
- VernacularTitle:纳豆粗提物抗兔高脂血症及抗氧化作用的研究
- Author:
Zhibian DUAN
;
Xiao JIANG
;
Hanhu JIANG
;
Shuxia ZHANG
;
Mingsheng DONG
;
Xiaoyan ZHAO
- Publication Type:Journal Article
- Keywords:
natto;
hyperlipidemia;
antioxidation
- From:
Acta Nutrimenta Sinica
1956;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the antioxidation and effects of water soluble extract from Natto on hyperlipidemia. Methods: The model of experimental hyperlipidemia was induced by high cholesterol diet. 18 rabbits were divided into 3 groups : model group, natto extract group and control group. Results: The natto extract could reduce the blood total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), malon-dialdehyde (MDA), atherogenic index (AI) of experimental rabbits 39.88% , 44.54% , 48.84%, 48.25% and 70.20%, respectively, and increase high density lipoprotein cholesterol (HDL-C), superoxide dismutase(SOD) 75.81% and 38.32%, respectively. Natto extract could prevent effectively the fatty degeneration of liver cells observed by pathological sections. Conclution: Natto extract can efficiently prevent the formation of experimental hyperlipidemia.
