EFFECT OF PHYTIC ACID ON COLORECTAL CARCINOGENESIS AND NATURAL KILLER CELL ACTIVITY IN RATS
- VernacularTitle:植酸对大鼠结直肠癌形成的抑制作用与NK细胞变化关系的探讨
- Author:
Zheng ZHANG
;
Yang SONG
;
Ketao LAN
- Publication Type:Journal Article
- Keywords:
phytic acid;
intestinal corcinoma;
natural killer cell
- From:
Acta Nutrimenta Sinica
1956;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effect of phytic acid (PHA) on 1,2-dimethylhydrazine (DMH) induced colorectal carcinogenesis in rats. Methods: Thirty four weeks old healthy male Wistar rats were randomly divided into two groups,control group given basal diet and PHA group given basal diet plus 2% sodium phytate solution. Both groups were injected DMH weekly for 20 w and then killed . Body weight, mortality, tumour incidence and average size, and natural killer(NK)cell activity were measured. Result: The mortality was lower in PHA group (P
