Pancreatic encephalopathy and Wernicke's encephalopathy in association with acute pancreatitis: 10 cases report
- VernacularTitle:急性胰腺炎并发的胰性脑病和韦尼克脑病10例报告
- Author:
Guohui SUN
;
Yunsheng YANG
;
Qingsen LIU
- Publication Type:Journal Article
- Keywords:
Acute pancreatitis;
Pancreatic encephalopathy;
Wernicke's encephalopathy;
thiamine
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics and the treatment of pancreatic encephalopathy (PE) and Wernicke's encephalopathy (WE). Method A retrospective study was conducted on 596 cases of acute pancreatitis. Results There were 93 cases of severe acute pancreatitis (SAP),among them encephalopathy was discovered in 10 patients (1.7%). All 6 patients of PE developed in SAP (6.5%);3 patients died (3% of SAP,50% of PE). Four cases of WE developed in AP (0.7%);2 patients died (0.3% of AP,50% of WE). Two patients of WE were treated with parenteral thiamine (vitamin B_ 1 ),and they survived. Conclusions PE occurred in early stage of SAP or recrudescence,while WE usually occurred in convalescent stage of SAP/AP. Long fasting,repeated vomiting,and total parenteral nutrition (TPN) without VitB_ 1 were main causes of VitB_ 1 deficiency,which might be the main causative factor in WE.
