Evaluation of the factors of long-term treatment in patients with gastroesophageal reflux disease
- VernacularTitle:胃食管反流病维持治疗方式的影响因素分析
- Author:
Xiaohong SUN
;
Meiyun KE
;
Zhifeng WANG
- Publication Type:Journal Article
- Keywords:
Gastroesophageal reflux disease Long-term treatment Endoscopy Esophageal manometry Esophageal pH monitoring
- From:
Chinese Journal of Practical Internal Medicine
2002;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate influencing factors of the long-term maintenance therapy in patients with gastroesophageal reflux disease (GERD).Methods 156 Patients with GERD were divided into on-demand therapy group and continuous therapy group by their treatment,according to symptom relief and improvement of quality of life in the course of therapy.The relationship between treatment and course,symptoms, esophageal motility,24-h pH monitoring and endoscopic findings were analysed.Results (1)5 Patients showed no response to acid suppression therapy and were excluded.For the 151 patients,92 were in on-demand therapy group,and 59 were in continuous therapy group.(2)The disease course and symptoms score in on-demand therapy group were significantly longer and higher than those of continuous therapy group (P