A novel histamine receptor: histamine H_4 receptor
- VernacularTitle:新型组胺受体:组胺H_4受体
- Author:
Hongshan WANG
;
Naiping WANG
;
Honghao ZHOU
- Publication Type:Journal Article
- Keywords:
histamine;
histamine H 4 receptor;
G-protein coupled receptor
- From:
Chinese Pharmacological Bulletin
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
HH 4R, a novel histamine receptor, was found in recent years. HH 4R posses unique pharmacological character and special tissue distribution,which has high homology compared with the H 3 receptor.In this article,we review various aspects of HH 4R,such as gene formation, tissue distribution, homologous analysis, signal transduction pathway, histamine ligand affinity,and so on, and preview future study on HH 4R.