Functional changes of the hypothalamus-pituitary-gonad axis in Tibetan male patients with chronic hepatic disease and its clinical significance
- VernacularTitle:藏族男性肝病患者下丘脑-垂体-性腺轴功能的变化及其临床意义
- Author:
Xuehong GONG
;
Lingyun SHAO
;
Wenhong ZHANG
- Publication Type:Journal Article
- Keywords:
Hepatic disease Hypothalamus-pituitary-gonad axis Gonadal hormone Tibetan
- From:
Chinese Journal of Practical Internal Medicine
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the variations of hypothalamus pituitary-gonad axis in Tibetan male patients with hepatic diseases and to understand the serum levels of gonadal hormone in different hepatic diseases.Methods We randomly selected 93 Tibetan male hepatic patients from Tibet Autonomous Region.The types of hepatic diseases included hepatitis A,hepatitis B,alcoholic hepatitis,cirrhosis and serious hepatitis.Meanwhile we selected 19 healthy Tibetan males as controls from the same region.We detected the serum levels of testoid (T),estradiol (E 2),follicle-stimulating hormone (FSH),luteinizing hormone (LH),prolactin (PRL) and luteinizing hormone-releasing hormone (LHRH).Statistical analysis was performed by double t-test.Results The serum levels of E 2,PRL and LHRH were all significantly different in patients with hepatic disease compared with the control.(P
