Expression of MMP-9 and E-cadherin in NSCLC and their prognostic value
- VernacularTitle:基质金属蛋白酶-9和上皮型钙粘附蛋白在非小细胞肺癌中的表达及其预后意义
- Author:
Jianmin HUO
;
Xiaohui XU
- Publication Type:Journal Article
- Keywords:
Matrix metalloproteinase-9 E-cadherin Non-small cell lung cancer
- From:
Chinese Journal of Practical Internal Medicine
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of the expression of matrix metalloproteinase-9(MMP-9) and E-cadherin(E-cad) in patients with non-small cell lung cancer (NSCLC).Methods Immunohistochemical method (SP) was used to detect the expression of the MMP-9 and E-cad in 62 NSCLC tissues and 18 normal lung tissues.Results The positive expression rate of MMP-9 and the abnormal expression rate of E-cad in NSCLC were closely related to the TNM stages,pathological grades and lymph node involvement (P