EFFECT OF COMPOUND ANTIOXIDANTS ON POSTPRANDIAL GLUCOSE AND INSULIN OF TYPE 2 DIABETES MELLITUS PATIENTS
- VernacularTitle:复合抗氧化剂对糖尿病人餐后血糖及血胰岛素水平的影响
- Author:
Cuifeng ZHU
;
Fan ZHANG
;
Wei LAN
;
Xiaoyan XU
;
Songchao GUO
;
Yixiang SU
- Publication Type:Journal Article
- Keywords:
antioxidant compound;
soy isoflavone;
diabetes mellitus
- From:
Acta Nutrimenta Sinica
1956;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the co-effect of antioxidant compound, soybean isoflavone (SI), VC and VE on glucose and insulin response after oral glucose load in Type 2 Diabetes Mellitus (T2DM) . Methods: 96 selected T2DM patients (50% male, 50% female) were randomly divided into 4 groups according to the dosage of the compound given , none (group B), low dosage (group C), medium dosage (group D) and high dosage (group E) . The normal control (group A) included 24 persons half male, half female . Blood glucose and insulin were determined at OGTT 0 h, 1 h, 2 h, 4 h, 6 h, and the areas under the curve (AUC) of blood insulin/glucose were calculated. Results: The AUC of blood insulin/glucose of male was higher than female in control group, but both were lower than those of four diabetes groups. In both genders of the diabetes groups, blood insulin AUC of group C, D, E was lower than group B, blood glucose AUC of group D, E was lower than group C and B. There was significant difference in blood insulin and glucose AUC of group E as compared to group B in female (P
