Changes of NSE and D-dimer in blood from neonates with hypoxic ischemic encephalopathy and their chinical values
- VernacularTitle:血液中NSE、D-二聚体变化在新生儿缺氧缺血性脑病中的临床价值
- Author:
Qiong CHEN
;
Zhi HUANG
;
La LIU
- Publication Type:Journal Article
- Keywords:
hypoxic ischemic encephalopathy;
neuron specific enolase;
D dimer
- From:Journal of Third Military Medical University
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the variation of neuron specific enolase (NSE) and D dimer in blood from neonates with hypoxic ischemic encephalopathy (HIE), and to explore the correlation of NSE and D dimer with brain damage. Methods NSE and D dimer levels in blood from neonates with HIE were measured by ELISA and turbidimetry before and after therapy. Results Blood NSE and D dimer levels in all objective cases were significantly higher than those in the control cases at 1 d after HIE and 5 d after therapy ( t =2.18-15.17, P