Effects of hyperuricemia on vascular endothelial function
- VernacularTitle:高尿酸血症对血管内皮功能影响的观察
- Author:
Haiyu YANG
;
Yujie ZENG
;
Zhanjun HUANG
- Publication Type:Journal Article
- Keywords:
Hyperuricemia Endothelium Vasodilation
- From:
Chinese Journal of Practical Internal Medicine
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of hyperuricemia on vascular endothelial function.Methods With high-resolution ultrasound,flow-and nitroglycerin induced dilation,the vasodilation of brachial artery was measured in 30 hyperuricemia male patients and 30 healthy male subjects(control group).Both serum NO and plasma endothelin-1(ET-1) levels were determined at the same time.Results In patients with hyperuricemia,flow-induced vasodilation was much reduced compared with that in the control subjects(P0.05).Plasma NO level in the hyperuricemia group was lower than that in the control group (P
