Blood pressure regulation of statins
- VernacularTitle:他汀类药物的血压调节作用
- Author:
Xiaojing XIE
;
Ancai WANG
- Publication Type:Journal Article
- Keywords:
statins;
hypertension;
plasma lipid abnormalities;
endothelial function;
angiotensin II receptors
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Statins is first choice of hypercholesteroiemia. Recently, clinical investigations have shown that statins can correct blood pressure in hypertension patients accompanied with lipid abnormalities. This result can be observed not only in untreated patients but also in patients treated with antihypertensive drugs. But some researches did not support this result completely. To some extend, the mechanisms responsible for the hypotensive effect seem to be largely independent on the effect of statins on lipid profile, and may be related to the improvement of endothelial function and the regulation of angiotensin II receptors.
