Protective effects of deproteinized extract of calf blood on hypoxia-reoxygenation-induced injury in cultured myocardial cells
- VernacularTitle:小牛血去蛋白提取物注射液对培养的心肌细胞缺氧再给氧损伤的保护作用
- Author:
Yuhong YANG
;
Fengxia LOU
;
Hongxin WANG
- Publication Type:Journal Article
- Keywords:
myocardial cells;
cultured;
deproteinized extract of calf blood;
hypoxia-reoxygenation-induced injury
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM : To explore the effects of DECB (deproteinized extract of calf blood, DECB) on hypoxia-reoxygenation-induced injury in cultured cardiac myocytes. METHODS : By using cultured myocardial cells as models, thenumber of death cells, beating frequency and the content of LDH were observed after hypoxia-reoxygenation-induced injury. RESULTS : 0.1 and 0.3 g?L -1 of DECB decreased the number of death cells and the content of lactate dehydrogenase (LDH), and restored the cellular beating frequency in the supernatant. CONCLUSION : DECB can protect the cultured myocardial cells against hypoxia-reoxygenation-induced injury.
