EFFECT OF ALOE ON THE PEROXIDITIVE DAMAGE MODEL IN MICROSOME
- VernacularTitle:芦荟对大鼠肝微粒体脂质过氧化损伤体外模型的影响
- Author:
Hongli CHEN
;
Xujun QIN
;
Chunxu HAI
;
Haiyang WANG
;
Jing HE
- Publication Type:Journal Article
- Keywords:
aloe;
microsome;
reactive oxygen species;
antioxidants;
malondialdehyde(MDA)
- From:
Acta Nutrimenta Sinica
1956;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investagate the antioxidative action of aloe and its dose-effect relationship. Methods:Sprague-Dawley rats were killed and then the livers were removed to isolate the microsome which can generate the reactive oxygen species in the presence of VC and Fe2+ or cumene hydroperoxite(CHP). In these peroxidative damage models, different dosages of aloe extract were added. Then the contents of malondialdehyde (MDA) were examined for analyzing the antioxidative action of aloe extract. Results:In CHP model, the content of MDA in those groups with different dosages of aloe extract decreased significantly (P
