A prospective evaluation with T~*_2W first-pass perfusion MRI in diagnosing breast neoplasm
- VernacularTitle:MR重T_2W首次通过灌注成像鉴别乳腺良恶性肿瘤的价值初探
- Author:
Xiaojuan LIU
;
Renyou ZHAI
;
Tao JIANG
;
Li WANG
- Publication Type:Journal Article
- Keywords:
Breast neoplasm;
Magnetic resonance imaging;
Diagnosis, differential
- From:
Chinese Journal of Radiology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To undergo T 2 *-weighted first-pass perfusion imaging after dynamic contrast-enhanced T 1-weighted imaging at the same examination in patients with breast neoplasm, and to evaluate if T 2 *-weighted imaging can provide additional diagnostic information to that obtained with T 1-weighted imaging. Methods Twenty-nine patients with breast lesions verified by pathology(benign 12, malignant 17)underwent MR imaging with dynamic contrast-enhanced T 1-weighted imaging of the entire breasts, then followed immediately with six-sections, T 2 *-weighted first-pass perfusion imaging of the lesions.The diagnostic indices were got by the 3 D T 1-weighted enhancement rate criterion and T 2 * signal intensity loss rate criterion individually.The sensitivity and specificity were calculated and the two methods were compared.Results With the dynamic contrast-enhanced T 1-weighted imaging, there was a significant differences between the benign and malignant breast lesions (t=2.563,P=0.016), but a considerable overlap of the signal intensity increase between the carcinomas and benign lesions was found, with a sensitivity of 94% and a specificity of 25%.With T 2 *-weighted first-pass perfusion imaging, there was a very significant differences between the benign and malignant breast lesions (t=4.777,P
