EFFECTS OF ENZYMOLYTIC EXTRACTS OF ABALONE ON LEARNING AND MEMORY IN MICE
- VernacularTitle:鲍鱼酶法提取液对小鼠学习和记忆的改善作用
- Author:
Wenduo PENG
;
Qiliang CHEN
;
Jinhu ZHAO
- Publication Type:Journal Article
- Keywords:
abalone;
enzymolytic extracts of abalone;
water extracts of abalone;
learning;
memory
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effects of enzymolytic extracts of abalone (EEA) on memory of mice, and compared with water extracts of abalone (WEA). Methods: Mice were given EEA or WEA once daily lasting 10 d. Their step-down latency (SDL) and escape latency (EL) in a passive avoidance , and food-hunting time in a maze were determined. Results: EEA 2-8 ml/kg lengthened SDL by 13.7 %-105.3 %, shortened EL by 40.0 %-60.0 % and food-hunting time by 28.3 %-49.4 %, in a dose-dependent manner. EEA reversed ethanol-induced disturbance of memory retrial in a passive avoidance and NaNO2-induced disruption of memory retention in a passive avoidance and maze. Significant action of WEA was not observed until the dose of WEA was increased to 8 ml/kg. Conclusion: EEA improves learning and memory, more effective than WEA.
