Expression of C-erbB-2 and Ki-67 in thyroid tumor and its clinical significance
- VernacularTitle:C-erbB-2和Ki-67在甲状腺肿瘤中的表达及临床意义
- Author:
Jimin CHENG
;
Zhanguo HE
;
Yanli LIU
- Publication Type:Journal Article
- Keywords:
Thyroid carcinoma;
thyroid adenoma;
C-erbB-2;
Ki-67
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of C-erbB-2 and anti-nuclear antigen Ki-67 in thyroid tumor, and its significance in pathologic diagnosis and prognosis the patient. Methods SP immunohistochemical technique was used to detect the expression of C-erbB-2 and Ki-67 in thyroid tissue of 90 cases of thyroid carcinoma and 20 cases of thyroid adenoma. Results High expression of both C-erbB-2 and Ki-67 in thyroid carcinoma, and their expression was weak in thyroid adenoma. The positive rate of C-erbB-2 expression in thyroid carcinoma was statistically higher than that in thyroid adenoma (48.9% vs 20.0%, P
