Successful treatment of pulmonary metastases of malignant fibrous histiocytoma with ZD1839: a case report
- VernacularTitle:ZD1839治疗恶性纤维组织细胞瘤术后两肺转移1例报告
- Author:
Kang ZHANG
;
Rongcheng LUO
;
Jianming XIE
- Publication Type:Journal Article
- Keywords:
malignant fibrous histiocytoma;
ZD1839;
molecular target therapy
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Malignant fibrous histiocytoma (MFH) is a common soft tissue sarcoma, which shows a strong predilection for distant metastases. Due to its limited response to radiotherapy and chemotherapy , poor prognosis is generally observed. A patient with MFH, who developed pulmonary metastases, postoperatively took ZD1839, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, because it was found that there was EGFR expression on the surface of the tumor cells. After a course of treatment (28 days), the pulmonary metastases disappeared, and the patient enjoyed a complete remission.
