Dynamic changes of BALF and serum IL-8 and IL-6 levels in patients with lower respiratory tract infection.
- VernacularTitle:下呼吸道感染患者血清与肺泡灌洗液白细胞介素-8、白细胞介素-6的动态监测
- Author:
Yanming HUANG
;
Wanli ZUO
;
Kangxin ZHANG
- Publication Type:Journal Article
- Keywords:
Infection,respiratory Interleukin-8 Interleukin-6 Neutrophils Macrophages,alveolar
- From:
Chinese Journal of Practical Internal Medicine
2003;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between interleukin-8 (IL-8),interleukin-6 (IL-6) and pathogenesis of lower respiratory infection(RI).Methods Bronchoalveolar lavage fluid (BALF) and serum IL-8,IL-6 levels were detected by enzyme linked immunosorbent assay (ELISA) in 36 patients with lower RI,28 patients with unstable asthma and 12 controls. Neutrophils (PMN) and alveolar macrophages (AMs) of BALF were examined.Results The levels of serum IL-8 and IL-6 of RI before treatment were significantly higher than those of RI after treatment,of unstable asthma,and of controls (P
