Delayed transverse radiation myelitis in esophageal carcinoma
- VernacularTitle:食管癌放射治疗后迟发横贯性放射性脊髓炎
- Author:
Yukui ZHAO
;
Guangyuan CHENG
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms/radiotherapy;
Radiomyelitis
- From:
Chinese Journal of Radiation Oncology
2003;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevention and treatment of delayed transverse myelitis caused by radiotherapy in patients with thoracic esophageal carcinoma . Methods Radical radiotherapy had been given to five patients (female 3,male 2) with thoracic esophageal carcinoma with delayed transverse myelitis developed 7 to 30 months after radiotherapy without any local recurrence.The study was done in an attempt to describe the clinical symptoms and signs.Analysis of causes was done to seek possible means of treatment and prevention.Results Once delayed transverse myelitis had happened,it was not possible to cure. In this group, four patients died 1-2 years after myelopathy had accurred , and one was alive with functional neurologic loss. Conclusions Delayed transverse myelitis is an uncommon and serious complication induced by irradiation. It is very difficult to manage and indicates a very poor prognosis. We recommend prucise radiation design and prudent performance for prevention.
