CHANGES OF ACTIVITIES OF LIPO-RELA TED ENZYMES IN VENTROMEDIAL HYPOTHALAMIC OBES E RATS AT ACUTE PHASE IN FED STATE
- VernacularTitle:下丘脑腹内侧核损伤性肥胖大鼠急性期脂肪代谢相关酶活性研究
- Author:
Zixin ZHENG
;
Jihong QIU
;
Junying TENG
;
Rongxin ZHANG
;
Changyong XUE
- Publication Type:Journal Article
- Keywords:
ventromedial hypothalamus(VMH);
obesity;
lipid metabolism
- From:
Acta Nutrimenta Sinica
1956;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate activities of lipo-related enzymes in ventromedial hypothalamic obese rats at acute phase in fed state. Methods: Female SD rats were divided into two groups, one group received bilateral electrolytic lesions of ventromedial hypothalamus(VMH), and another one was used as sham control. Samples of blood, livers, and subcutaneous, parametric and mesenteric adipose tissues ,and gastrocnemius were collected one week after VMH lesions and sham operations in fed state. Results: Serum insulin in VMH group was higher than that in sham group, meanwhile serum free fatty acids in VMH group were lower (P