Helicobacter pylori and gastric carcinoma
- VernacularTitle:幽门螺杆菌与胃癌
- Author:
Bo SUN
;
Hua YANG
;
Zhenxing TU
;
Zhaoshen LI
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
stomach neoplasms;
review literature
- From:
Academic Journal of Second Military Medical University
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Helicobacter pylori(Hp) infection plays an important role in the development of gastric carcinoma. Colonization of CagA-positive Hp is a great risk for intestinal gastric carcinoma. The mechanism of Hp infection changing the gastric epithelium at the molecular level is complex and through multiple pathways. Animal models can be of great help in exploring the role of Hp infection in gastric cancer development. This paper reviewed the latest studies of epidemiology, animal model and molecular pathogenesis of Hp associated gastric cancer.
