Membrane transporters and drug resistance of Candida albicans
- VernacularTitle:膜转运蛋白与白念珠菌抗药
- Author:
Yan WANG
;
Yongbing CAO
;
Pinghui GAO
;
Yuanying JIANG
- Publication Type:Journal Article
- Keywords:
Candida albicans;
drug resistance;
membrane transporters;
review literature
- From:
Academic Journal of Second Military Medical University
1999;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of candidiasis caused by Candida albicans has increased dramatically in recent years. With the widespread use of antifungal agents, the emergence of drug resistant strains pose a major challenge to drug treatment. The overexpression of membrane proteins functioning as drug efflux pumps is one of the main mechanisms for multidrug resistance of Candida albicans. Membrane transporters associated with drug resistance in Candida albicans are reviewed in this article.