Radiotherapy of stage I and II non-small cell lung cancer in 168 patients
- VernacularTitle:168例Ⅰ和Ⅱ期非小细胞肺癌放射治疗疗效观察
- Author:
Yaping XU
;
Xiao ZHENG
;
Shenglin MA
;
Xiuyong CHEN
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small cell lung/radiotherapy;
Prognosis
- From:
Chinese Journal of Radiation Oncology
1992;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and prognostic factors of radiotherapy in 162 patients with stage I and II non-small cell lung cancer(NSCLC).Methods Between December 1982 and August 1992, 168 patients with stage I and II NSCLC were treated, with 116 confirmed by histopathology and 52 by cytopathology. All patients received radiotherapy to a dose of 40-76 ?Gy and were followed up for more than five years. Results The overall 1-, 3- and 5-year survival rates were 67.6%, 28.0% and 15.7%. Absence of concurrent disease and Karnofsky performance status ≥80 were favorable prognostic factors. Conclusions Radiotherapy is effective for stage I and II non-small cell lung cancer patients who are contraindicated for surgery. Higher dose of radiotherapy is recommended to improve the local control and survival rate.