Study of immunological function in severe acute respiratory syndrome
- VernacularTitle:严重急性呼吸综合征的细胞免疫功能研究
- Author:
Hao WU
;
Yonghong ZHANG
;
Xinyue CHEN
- Publication Type:Journal Article
- Keywords:
Severe acute respiratory syndrome;
Immunity, cellular;
Antigens, CD3;
Antigens, CD4;
Antigens, CD8
- From:
Chinese Journal of Infectious Diseases
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the relationship between disease progress with the change of cell im munological function as well as the effect of immunological function in severe a cute respiratory syndrome. Methods Retrospective study was designed to analyze the relationship of disease progres s with the change of immunological function. According to the disease outcomes, the patients are divided into two groups: died group and survival group. The dif feren ce of immunological function in groups was performed statistics analysis. Results Immunological function (CD3 +, CD4 +, CD8 +) descended to the lowest level in period of fastigium in SARS patient, and then recovery quickly. Comparison of died grou p and survival group was found that Immunological function (CD3 +T, CD4 +T, CD 8 +T) were lower in period of fastigium and recovery in died group than in survival g roup(P
