Influence of Helicobacter pylori infectoin and smoking on serum pepsinogen levels in gastric adenocarcinoma.
- VernacularTitle:幽门螺杆菌感染和吸烟对胃腺癌患者胃蛋白酶原水平的影响
- Author:
Youcai ZHANG
;
Changsheng DENG
;
Youqing ZHU
- Publication Type:Journal Article
- Keywords:
Gastric adenocarcinoma Helicobacter pylori Smoking Pepsinogen
- From:
Chinese Journal of Practical Internal Medicine
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the influence of Helicobacter pylori (H.pylori) and smoking on serum pepsinogen (PG) levels in gastric adenocarcinoma (GAC).Methods Serum PGⅠand PGⅡ levels were measured by using radioimmunoassay method;H.pylori infection was determined by Hp-IgG antibodies in stored serum samples by using enzyme-linked immunosorbent assay and 14C urea breath test.Results In H.pylori negative cases,the serum PGⅠmean level in current smoking GACs was significantly increased compared with those non-smoking or ever-smoking GACs (the former:t=2.709,P