THE HYPOGLYCEMIC EFFECT AND IMPROVEMEMT OF DIABETIC SYMPTOMS BY TEA POLYSACCHARIDE IN MICE
- VernacularTitle:茶多糖降血糖、改善糖尿病症状作用的研究
- Author:
Jianguo CHEN
;
Yin WANG
;
Song MEI
;
Weiqi LAI
;
Ying FU
;
Xin HU
- Publication Type:Journal Article
- Keywords:
tea polysaccharide;
alloxan;
diabetes;
blood glucose;
diabetic symptoms.
- From:
Acta Nutrimenta Sinica
1956;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effects of tea polysaccharide (TP) on blood glucose and diabetic symptoms in mice. Methods: Alloxan-induced diabetic mice were divided into 4 groups, and administered orally with saline, TP at doses of 1.0, 2.0, 4.0 g/kg body weight, respectively for 4 weeks. Water intake and body weight were recorded daily and weekly respectively.Fasting blood samples were collected for measurement of glucose at the end of 2nd and 4th week.Results: Symptoms of diabetic mice fed TP were improved obviously. Their blood glucose concentration and water intake decreased significantly. On the other hand, their body weight increased obviously. There was positive correlation between blood glucose and water intake, but negative correlation between water intake and body weight. Conclusion: TP can decrease blood glucose concentration and improve diabetic symptoms in mice.
