MEASUREMENT AND EVALUATION OF SERUM SEX HORMONES IN PATIENTS WITH SEVERE ACUTE RESPIRATORY SYNDROME (SARS)
- VernacularTitle:严重急性呼吸综合征患者血清性激素水平的测定和评价
- Author:
Wei WANG
;
Yixiu YE
;
Hongmin LI
- Publication Type:Journal Article
- Keywords:
severe acute respiratory syndrome;
estradiol;
progesteron;
follicle-stimulating hormone;
sex hormones
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the levels of serum sex hormone in patients with severe acute respiratory syndrome (SARS), in order to determine whether there were involvement of sex glands. Methods The levels of serum E2, PROG, FSH, LH and PRL were measured in 66 patients with severe acute respiratory syndrome (SARS) by electrochemiluminescence, and the results were compared with that of controls. Results The results showed that levels of serum E2, PROG,and FSH in patients with SARS were significantly lower than those of controls. On the other hand, the levels of serum LH and PRL were significantly higher than those of controls. The level of E2 in patients with severe type SARS was significantly lower than that in patients with mild type.The levels of sex hormones returned later than improvement of clinical symptoms. Conclusion The levels of serum sex hormones were lowered in patients with SARS, indicating that the changes in sex hormones might play a role in the disease process of SARS. Recovery of levels of sex hormones was retarded.
