EFFECT AND MECHANISM OF ARGININE VASOPRESSION (AVP) ON SECRETION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) BY ENDOTHELIAL CELLS
- VernacularTitle:精氨酸加压素对血管内皮细胞分泌VEGF的影响
- Author:
Zhongyan LI
;
Dan CHEN
;
Jixian YE
- Publication Type:Journal Article
- Keywords:
arginine vasopression;
endothelial growth factor;
endothelium, vascular
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the effect of arginine vasopression (AVP) on the secretion of vascular endothelial growth factor (VEGF) by vascular endothelial cell (VEC). VEC of human greater omentum artery were isolated and cultured. The concentrations of VEGF and activity of protein kinase C (PKC) in the culture medium were measured. Results indicated that after the cells were incubated with 1?10 -9～1?10 -7mol/L AVP for 6 hours, the concentration of VEGF and activity of PKC were markedly increased compared to control (P
