Immune enhancing effect of arginine on patients with chronic obstructive pulmonary disease complicated with malnutrition.
- VernacularTitle:精氨酸对慢性阻塞性肺疾病合并营养不良的免疫调理作用
- Author:
Weiguo XU
;
Yong LUO
;
Ling YANG
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease L-arginine Nutritional support Immune modification
- From:
Chinese Journal of Practical Internal Medicine
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the immune enhancing effect of arginine on patients with chronic obstructive pulmonary disease (COPD) complicated with malnutrition.Methods Thirty cases with COPD accompanied by malnutrition received nutritional support of total calorie intake of 1 5 times of resting energy expenditure (REE).Group A(n=12) received oral administration of 30g L-arginine per day as supplementation;Group B(n=18) were control subjects.Results The nutritional parameters such as TSF(triceps skinfold) thickness,PAlb(prealbumin),CHI(creatine height index) were markedly improved in Group A than Group B,TNF-?,CD 8 decreased and IL-2,NO(nitric oxide),IgG and CD 4 increased significantly in Group A(P