Research progress of platelet-rich plasma in cartilage regeneration
10.3760/cma.j.issn.1673-4181.2013.01.015
- VernacularTitle:富血小板血浆在软骨修复领域的研究进展
- Author:
Zhongshan WHANG
;
Haiyan QIN
;
Yimin ZHAO
- Publication Type:Journal Article
- Keywords:
Platelet-rich plasma;
Cartilage regeneration;
Articular cartilage;
Defects;
Platelet-rich gel
- From:
International Journal of Biomedical Engineering
2013;(1):61-64,后插1
- CountryChina
- Language:Chinese
-
Abstract:
Cartilage is vulnerable to traumatic injury and unable to facilitate a satisfactory healing response due to its poor vascularity and inability to access mesenchymal stem cells.Continuous defects in the joint surfaces cause pain,swelling,and mechanical symptoms that result in functional impairment and limitation of athletic participation.Commonly used repair techniques include marrow stimulation,structural osteo-articular autografts or chondrocyte implantation.Platelet-rich plasma (PRP) is a concentrate extract of platelets from autologous blood,which is rich in growth factors and other cytokines and provides local environment for tissue regeneration and lends a possible option for the stimulation and acceleration of cartilage regeneration.This review gives summarization on the current state of the use of PRP for cartilage regeneration.
