Clinical and pathological charactcristics of ANCA associated systemic vasculitis with immune complex deposition in kidney
- VernacularTitle:肾脏有免疫复合物沉积的小血管炎的临床病理特点
- Author:
Feng YU
;
Minghui ZHAO
;
Wanzhong ZOU
;
Youkang ZHANG
;
Haiyan WANG
- Publication Type:Journal Article
- Keywords:
Antineutrophil cytoplasmic antibodies;
Immune complex
- From:
Chinese Journal of Nephrology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical and pathological characteristics of ANCA associated systemic vasculitis(AASV) with immune complex deposition in kidney and compare with that of pauci-immune AASV. Methods Patients with AASV, admitted in our hospital in last 5 years, were retrospectively studied. The clinical and pathological characteristics were compared between patients with immune complex deposition and patients with pauci-immune deposition. Results There were eitht patients with immune complex deposition (five with IgM deposition, two with IgA deposition and one with IgG deposition) and 32 patients with pauci-immune deposition. There was no significant difference in age, gender, type of ANCA, interval between onset of vasculitis and renal biopsy, clinical manifestations and short-term renal survival rate between the two groups. Patients with immune complex deposition had a higher predromal infection rate ( P
