Advances in study of new antiapoptosis factor:survivin
- VernacularTitle:凋亡抑制因子生存素的研究进展
- Author:
Yanping CHEN
;
Fuyong BI
- Publication Type:Journal Article
- Keywords:
review;
survivin;
tumor;
apoptosis;
angiogenesis
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Survivin has been identified recently as a unique member of the inhibitor of apoptosis protein family. It is expressed during fetal development and in all common human cancers, but not in normal tissues. It can inhibit apoptosis induced by a variety of factors and play an important role during angiogenesis. Being a universal tumor-specific antiapoptosis inhibitor, survivin may serve as a potential target for gene-protein-based therapy of tumor.
