Clinical study of low molecular weight heparins in treatment of chronic pulmonary heart diseases
- VernacularTitle:低分子肝素治疗慢性肺源性心脏病合并高凝状态的临床研究
- Author:
Ailian ZHOU
;
Henghua CHEN
;
Liangchun TANG
- Publication Type:Journal Article
- Keywords:
pharmacodynamics;
chronic pulmonary heart diseases;
hypercoagulability state;
low molecular weight heparins
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
1999;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effects and safe of low molecular weight heparins (LMWH) in the treatment of patients with chronic pulmonary heart diseases (CPHD) at hypercoagulability state. METHODS: 65 patients were randomly assigned to treatment group (n=33) and control group (n=32). All patients were given routine treatments. The patients of treatment group were hypodermically injected with 4 100～6 150 U of LMWH per day for 7 days as a course. RESULTS: After 7 days of the treatments, the patients of treatment group showed better curative effect and significantly increase in PaO_2 and AT-III and decrease in PaCO_2 and FIB in comparison with the patients in control group (P
