Clinical pathology and molecular genetics on familial amyloidotic polyneuropathy
- VernacularTitle:家族性淀粉样变性多神经病——附一家系临床、病理和分子遗传学研究
- Author:
Zhaoxia WANG
;
Ying ZHANG
;
Wei ZHANG
;
Yu YUAN
- Publication Type:Journal Article
- Keywords:
Amyloid neuropathies,familial/genet;
Gene;
Pedigree
- From:
Journal of Peking University(Health Sciences)
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
75%). Immunoglobulin ? and ? chains as well as TTR positive deposits were not demostrated in the accumulated amyloid material. There was neither TTR nor apolopoprotein A1 coding gene mutation detected in the proband and her son. Conclusion: The pathological findings demonstrated existence of a FAP. However, the immuno pathological and genetic results could not classified the type of this FAP family. Further genetic studies are required to identify it.
