Biologic function of p21~(WAF1/CIP1) gene and its association with carcinogenesis
- VernacularTitle:p21~(WAF1/CIP1)基因的生物学功能及其与肿瘤发生的关系
- Author:
Yaguang XI
;
Yinghui REN
;
Xiulan SU
;
Yang KE
- Publication Type:Journal Article
- Keywords:
p21 WAF1/CIP1;
Cell cycle;
Apoptosis;
Cell differentiation;
Neoplasms/genet
- From:
Journal of Peking University(Health Sciences)
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
p21 WAF1/CIP1 gene is known for a most important cell cycle regulator as well as its roles in apoptosis and differentiation. This review focuses on p21 WAF1/CIP1 gene functions and its association with carcinogenesis. Better understanding of the structure and function of p21 WAF1/CIP1 gene may help to comprehend molecular mechanisms of cancers and to facilitate diagnosis and treatment of malignancy.
