Premixed or basal insulin: the insulin initiation consideration in Chinese patients with type 2 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2013.05.026
- VernacularTitle:预混还是基础:中国2型糖尿病患者起始胰岛素治疗的思考
- Author:
Jun YANG
;
Jun LI
- Publication Type:Journal Article
- Keywords:
Diabetes;
Premixed insulin;
Basal insulin;
Hyperglycaemia;
β-cell dysfunction
- From:
Chinese Journal of Endocrinology and Metabolism
2013;(5):后插5-后插9
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] The general status of glycemic control and insulin initiation are not optimistic in Chinese patients with type 2 diabetes.Chinese patients experience pancreatic β-cell dysfunction and reduction of early phase insulin spike earlier and more severely compared to Caucasians.These can cause more significant postprandial hyperglycaemia which is further deteriorated by traditional carbohydrate-rich Chinese diet.Therefore,premixed insulin may be a more appropriate option of insulin initiation therapy for Chinese patients with type 2 diabetes mellitus.