Expression and significance of eotaxin in nasal secretions

VernacularTitle:Eo taxin在鼻腔分泌物中的表达及意义
Author: Ning LAN ; Hong XU
Publication Type:Journal Article
Keywords: eotaxin; nasal polyps; nasal secretions; enzyme-linked immunosorbent assay
From: Chongqing Medicine 2014;(3):288-289,292
CountryChina
Language:Chinese
Abstract: Objective To discuss the expression and significance of eotaxin in the nasal secretions of the patients with nasal pol-yps .Methods The nasal secretion samples were collected from 40 patients including 15 cases of nasal polyps ,15 cases of chronic si-nusitis and 10 cases of nasal septum deviation .The enzyme-linked immunosorbent assay(ELISA) was adopted to detect the concen-tration of eotaxin .Results The average concentration of eotaxin was (468 .82 ± 440 .64)pg/mL in nasal polyps ,(443 .85 ± 334 .68) pg/mL in chronic sinusitis and (149 .23 ± 49 .01)pg/mL in nasal septum deviation .The eotaxin concentrations in the nasal polyps group and the chronic sinusitis group were higher than those in the nasal septum deviation group ,the difference was statistically significant(P<0 .05) .Conclusion The eotaxin concentration in the nasal secretions of the patients with nasal polyps is significantly increaseed ,which might be concluded that eotaxin may play an important role in the occurrence and development process of nasal polyps .