RELATIONSHIP BETWEEN PLASMA PROCALCITONIN AND THE INTESTINAL MUCOSAL INJURY IN PATIENTS WITH LIVER CIRRHOSIS
- VernacularTitle:肝硬化患者血浆降钙素原与肠黏膜损伤的关系
- Author:
Wei ZHANG
;
Shilan ZHANG
;
Haibin WANG
- Publication Type:Journal Article
- Keywords:
liver cirrhosis;
procalcitonin;
injury, intestinal mucosa;
endotoxin;
diamine oxidase
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the relationship between plasma procalcitonin(PCT) level and intestinal mucosal injury in patients with liver cirrhosis(LC), plasma PCT levels in 78 patients with LC were determined by immunoluminometric assay, endotoxin(ET)and the indicator of intestinal mucosal injury-diamine oxidase(DAO)activity were measured by fluorometric assay, TNF-? and IL-6 were measured by ELISA. The results showed that plasma levels of all these factors in LC patients were significantly higher than those of normal controls, and they were also higher in spontaneous bacterial peritonitis (SBP) group than those in non SBP group(P