PROTECTIVE EFFECTS OF OFFSPRING OF MOTHER-MICE INFECTED WITH TRICHINELLA SPIRALIS AGAINST SCHISTOSOMA JAPONICUM INFECTIONS
- VernacularTitle:旋毛虫感染母鼠产小鼠抗血吸虫感染保护性的初步研究
- Author:
Fei PENG
;
Qiongyao HUANG
;
Nianmeng LIU
;
Fang FENG
;
Qi HU
- Publication Type:Journal Article
- Keywords:
Trichinella spiralis;
offspring;
Passive transfer;
Schistosoma japonicum;
Cercaria;
Protective immunity
- From:
Chinese Journal of Schistosomiasis Control
1989;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the acquired immunity against Schistosoma japonicum infections in the offspring of mother-mice infected with Trichinella spiralis.Methods The offspring of mother-mice infected with Trichinella spiralis and the mice after passively transferring the offspring's sera were sacrificed at day 42 post infection with S. japonicum cercariae. The percentage of reduction in worm burdens was calculated to determine the protective effects. Results Comparing with the control group, the reduction rates of the worm were 24.31% in the offspring, 18.65% and 20.77% in mice with passively transferring the offspring's sera by intravenous injection and muscular injection respectively. Conclusion The offspring of mother-mice infected with Trichinella spiralis and the mice with passively transferring the offspring's sera could acquire protective immunity against Schistosoma japonicum infections.
