Research update of gabapentin in neuropathic pain management
- VernacularTitle:加巴喷丁用于神经病理性疼痛治疗的研究进展
- Author:
Guokai LIU
;
Yuguang HUANG
;
Ailun LUO
- Publication Type:Journal Article
- Keywords:
pharmacodynamics;
review;
anticonvulsant;
gabapenti n;
neuropathic pain
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Gabapentin may bind the ? 2? subunit of the voltage -dependent calcium ion channels at the postsynaptic dorsal horn and interrupt t he series of events possibly leading to the experience of a neuropathic pain sen sation. Many clinical studies have clearly demonstrated the efficacy of gabapent in in the treatment of diabetic neuropathy and postherpetic neuralgia. Gabapenti n is considered an effective drug with its minimal side effects and drug interac tions in the management of neuropathic pain syndromes.
