Advances in inhibiting the expression of Bax and cytoprotec tion
- VernacularTitle:抑制Bax基因表达与细胞保护的研究进展
- Author:
Zhigang CAO
;
Shoujun YUAN
- Publication Type:Journal Article
- Keywords:
pharmacology;
review;
Bax gene;
apoptosis;
cytoprotection;
antisense nucleotides
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2000;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Apoptosis is involved in a variety of physiological and path ol ogical conditions. Bax is proapoptotic member in signal pathway of apoptosis. It will contribute to the survival of cells if reducing its expression and activit y. Advances in factors influencing Bax, biological effects induce d by Bax knock-out, and antisense nucleotides targeted to Bax-mRNA were r eviewed in this article during recent years.
