Systematic review of esophageal stents plus radiotherapy in the treatment of patients with inoperable esophageal cancer
10.3760/cma.j.issn.1006-9801.2013.09.013
- VernacularTitle:外放疗联合食管支架治疗不可手术食管癌患者的Meta分析
- Author:
Shengliang HE
;
Biao HAN
;
Minjie MA
;
Ning WEI
;
Kan YANG
;
Yu ZHANG
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Esophageal stents;
Radiotherapy;
Systematic review
- From:
Cancer Research and Clinic
2013;25(9):619-621,624
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficiency and safety of esophageal stents combined with radiotherapy compared with esophageal stents alone in the treatment of advanced esophageal cancer.Methods CBM,VIP,CNKI,Cochrane Library,Pubmed and Embase etc were searched by computer begining from the establishment of these datebases to December 2012.The related references as well as communicated with other researchers were also traced to obtain certain informations.Randomized and quasi-randomized controlled trials compared esophageal stents plus radiotherapy with esophageal stents alone in the treatment of advanced esophageal cancer were included.The statistical software RevMan 5.0 was used.Results Seven published articals were included (443 patients),and all trails methodological quality were grade C.The results of Metaanalysis showed that compared with esophageal stents along,esophageal stents combined with radiotherapy improve 1-year survival rates and reduce the local recurrence rates.Gastrointestinal bleeding rates,chest pain rates,gastro-esophageal reflux rates remained similarily.Conclusion Compared with esophageal stents along,esophageal stents combined with radiotherapy can improve 1-year survival rates and reduce the local recurrence rates.
