OXIDATIVE STRESS IN END STAGE RENAL DISEASE
- VernacularTitle:终末期肾病氧化应激状态的研究
- Author:
Min LIANG
;
Fanfan HOU
;
Jianwe TIAN
- Publication Type:Journal Article
- Keywords:
kidney failure, chronic;
dialysis;
oxidative stress
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
To observe changes in oxidative stress and effects of dialysis on patients with end stage renal disease (ESRD), vitamin E, GSH, malondialdehyde (MDA) levels in plasma and carbonyl contents of plasma proteins, and blood glutathione peroxidase (GPx) activity were assayed in healthy individuals, chronic renal failure (CRF) patients before dialysis, and after hemodialysis (HD) or peritoneal dialysis (PD). As compare with healthy control, plasma levels of vitamin E and GPx activity of CRF patients were lower, whereas plasma contents of both MDA and carbonyl content of plasma proteins were increased significantly ( P