Plasma adrenomedullin concentrations in patients with bronchial asthma and its clinical significance
- VernacularTitle:支气管哮喘患者血浆肾上腺髓质素的质量浓度及临床意义
- Author:
Juan ZHANG
;
Peizong SUN
;
Songyun OUYANG
- Publication Type:Journal Article
- Keywords:
Bronchial asthma Adrenomedullin
- From:
Chinese Journal of Practical Internal Medicine
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To investigate the clinical significance of plasma adrenomedullin (ADM) concentrations in patients with asthma.Methods The plasma ADM concentrations in 23 asthmatic patients with an acute attack and 18 asthmatic patients in remission stage were measured by radioimmunoassay.Linear regression analysis was used to evaluate the correlations between two variables.Twenty healthy subjects served as a normal control group.Results The plasma ADM concentrations in asthmatic patients with an acute attack [(28.73?7.12)ng/L]were significantly higher than those of stable asthmatic patients [(13.85?4.48)ng/L,P0.05).Conclusion The results suggest that ADM is involved in the pathophysiological process of acute asthma attack and may play an important role in the inflammation of asthmatic airways.
