Comparison of the therapeutic effects of HDR endobronchial brachytherapy and simple external irradiation on the treatment of lung cancer with atelectasis
- VernacularTitle:高剂量率腔内治疗与单纯外照射治疗癌性肺不张的疗效比较
- Author:
Dezhi LI
;
Qiming LI
;
Qing ZHANG
;
Shangzhi FU
- Publication Type:Journal Article
- Keywords:
lung cancer;
atelectasis;
endobronchial brachytherapy;
extemal irradiation
- From:Journal of Third Military Medical University
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Objective To investigate the clinical application of high-dose-rate(HDR)endobronchial brachytherapy for the treatment of primary lung cancer with atelectasis. Methods A total of 142 cases of lung cancer with atelectasis treated with HDR endobronchial brachytherapy and 71 cases(contr01)treated with extemal irradiation only at onr center of cancer were comparatively studied.1n the treatment group,with the aid of bmnchoscope,brachytherapy was applied 2 or 3 times at the dose of 8 Gy each time to a tissue depth of 1 to 1.5 cm.Cases in the contmlgroup,treated with external irradiation,received 60-70 Gy in total.Results Complete recruitment of atelectasis was observed in 80.28%cases of the treatment group and 64.79%in the control,T11ere Was significant difference between the two groups.Survival rates after 1,2 and 3 years in cases with complete remission of atelectasis in treatment group were 60.68%,44.44%and 23.93%,but 36.00%,28.00%and 16.00%in cases with no remission of atelectasis.Significant difference of one-year survival Was found between the two groups(P
