Research development in the effect of reactive oxygen species on protein kinase and gene expression
- VernacularTitle:活性氧对蛋白激酶和基因表达调节作用的研究进展
- Author:
Decheng REN
;
Guanhua DU
- Publication Type:Journal Article
- Keywords:
ROS;
protein kinases;
gene expression;
redox-sensitive enzymes
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Reactive oxygen species (ROS) play a very important role in vascular homeostasis both physiologically and pathophysiologically. The imbalance between production and metabolism of ROS contributes to various vascular diseases. Recent studies have demonstrated that ROS regulated the redox-sensitive protein kinases in the signal transduction pathways,affected the activities of these kinases, and thus modulated the gene expression.
