Effect of yishenjiangzhuo decoction on NE,5-HT contents of hippocampus in cerebral ischemia reperfusion rats
- VernacularTitle:益肾降浊汤对脑缺血再灌注大鼠海马NE、5-HT含量的影响
- Author:
Weijuan GAO
;
Tao QIAN
;
Bi CONG
- Publication Type:Journal Article
- Keywords:
Yishenjiangzhuo decoction;
cerebral ischemia reperfusion;
hippocampus;
NE, 5-HT;
rat
- From:
Chinese Pharmacological Bulletin
1986;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM To observe the effect of Yishenjiangzhuo decoction on the NE,5-HT contents of hippocampus in cerebral ischemia reperfusion rats. METHODS High pressure lipuid chromatography-electrochemical process was used to measure the NE and 5-HT contents on the d 1, d 7 and d 15 after cerebral ischemia reperfusion by common carotid artery occlusion. RESULTS The NE contents of hippocampus were respectively 364.25?66.47, 349.76?59.38, (344.59?70.31) ?g?g -1 and the 5-HT contents were respectively 646.72?83.33,629.11?90.64,(596.68?99.47) ?g?g -1 on the d 1, d 7 and d 15 in the model group, which significantly decreased compared with the control group( P
